default Targeted inhibition of cooperative mutation- and therapy-induced AKT activation in AML effectively enhances response to chemotherapy - Leukemia Populær

1274 downloads

Estruch M, Reckzeh K, Vittori C, Centio A, Ali M, Engelhard S, Zhao L, Won KJ, Liu P, Porse BT, Theilgaard-Mönch K.

default Improved Outcomes After Allogenic Hematopoietic Stem Cell Transplantation With Fludarabine/Treosulfan for Patients With Myelodysplastic Syndromes. Biol Blood Marrow Transplant Populær

1408 downloads

Eileen Wedge, Henrik Sengeløv, Jakob Werner Hansen, Niels Smedegaard Andersen, Ida Schjødt, Søren Lykke Petersen, Brian Kornblit, Kirsten Grønbæk, Lone Smidstrup Friis

default Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact. PLoS One Populær

1363 downloads

Schönherz AA, Bødker JS, Schmitz A, Brøndum RF, Jakobsen LH, Roug AS, Severinsen MT, El-Galaly TC, Jensen P, Johnsen HE, Bøgsted M, Dybkær K

default The prognostic effect of smoking status on intensively treated acute myeloid leukaemia - A Danish nationwide cohort study. Br J Haematol Populær

1277 downloads

Daniel Kristensen, Lars B Nielsen, Anne S Roug, Tove-Christina C Kristensen, Tarec C El-Galaly, Jan M Nørgaard, Claus W Marcher, Claudia Schöllkopf, Kim Theilgaard-Mönch, Marianne T Severinsen

default Addressing the room for improvement in management of acute promyelocytic leukemia Populær

1534 downloads

Jan M Nørgaard, Lone S Friis, Jørgen S Kristensen, Marianne T Severinsen, Ingolf Mølle, Claus W Marcher, Peter Møller, Claudia Schoellkopf, Ove J Nielsen, Birgitte S Preiss, Mette K Andersen, Eigil Kjeldsen, Bruno C Medeiros, Lene S G Østgård

default Stringent or nonstringent complete remission and prognosis in acute myeloid leukemia: a Danish population-based study. Blood Adv. Populær

2694 downloads

Øvlisen AK, Oest A, Bendtsen MD, Bæch J, Johansen P, Lynggaard LS, Mølle I, Mortensen TB, Weber D, Ertner G, Schöllkopf C, Thomassen JQ, Nielsen OJ, Østgård LSG, Bøgsted M, Dybkær K, Johnsen HE, Severinsen MT

default Evolution of relative survival for acute promyelocytic leukemia patients alive at landmark time-points: a population based study. Leukemia Populær

2244 downloads

Biccler J, Østgård L, Severinsen M, Marcher C, Møller P, Schöllkopf C, Friis LS, Boegsted M, Jakobsen L, El_Galaly T, Nørgaard JM

default A randomized assessment of adding the kinase inhibitor lestaurtinib to first-line chemotherapy for FLT3-mutated AML. Blood Populær

2596 downloads

Knapper S, Russell N, Gilkes A, Hills RK, Gale RE, Cavenagh JD, Jones G, Kjeldsen L, Grunwald MR, Thomas I, Konig H, Levis MJ, Burnett AK.

default Risks of bleeding and thrombosis in intensive care unit patients with haematological malignancies. Ann Intensive Care Populær

2667 downloads

Russell L, Holst LB, Kjeldsen L, Stensballe J, Perner A.

default Effects of Education and Income on Treatment and Outcome in Patients With Acute Myeloid Leukemia in a Tax-Supported Health Care System: A National Population-Based Cohort Study. JCO Populær

2346 downloads

Østgård LSG, Nørgaard M, Medeiros BC, Friis LS, Schoellkopf C, Severinsen MT, Marcher CW, Nørgaard JM.

default Improved outcome in acute myeloid leukemia patients enrolled in clinical trials: A national population-based cohort study of Danish intensive chemotherapy patients. Oncotarget Populær

2477 downloads

Østgård LS, Nørgaard M, Sengeløv H, Medeiros BC, Kjeldsen L, Overgaard UM, Severinsen MT, Marcher CW, Jensen MK, Nørgaard JM.

default Cytomorphology review of 100 newly diagnosed lower-risk MDS patients in the European LeukemiaNet MDS (EUMDS) registry reveals a high inter-observer concordance. Ann Hematol Populær

2427 downloads

de Swart L, Smith A, MacKenzie M, Symeonidis A, Neukirchen J, Mikulenková D, Vallespí T, Zini G, Paszkowska-Kowalewska M, Kruger A, Saft L, Fenaux P, Bowen D, Hellström-Lindberg E, Čermák J, Stauder R, Tatic A, Holm MS, Malcovati L, Mądry K, Droste J, Blijlevens N, de Witte T, Germing U.

default Vitamin C increases viral mimicry induced by 5-aza-2′-deoxycytidine Populær

3841 downloads

Minmin Liua, Hitoshi Ohtania, Wanding Zhoua, Andreas Due Ørskov, Jessica Charletc, Yang W. Zhangd, Hui Shena, Stephen B. Baylina, Gangning Liangc, Kirsten Grønbæk, and Peter A. Jones

default Assessment of Minimal Residual Disease in Standard-Risk AML. NEJM Populær

3662 downloads

Ivey A, Hills RK, Simpson MA, Jovanovic JV, Gilkes A, Grech A, Patel Y, Bhudia N, Farah H, Mason J, Wall K, Akiki S, Griffiths M, Solomon E, McCaughan F, Linch DC, Gale RE, Vyas P, Freeman SD, Russell N, Burnett AK, Grimwade D; UK National Cancer Research Institute AML Working Group.

default The Danish National Acute Leukemia Registry. J Clin Epidemiology Populær

3792 downloads

Granfeldt Østgård LS, Nørgaard JM, Raaschou-Jensen KK, Pedersen RS, Rønnov-Jessen D, Pedersen PT, Dufva IH, Marcher CW, Nielsen OJ, Severinsen M, Friis LS

default Toxicity profile and treatment delays in NOPHO ALL2008-comparing adults and children with Philadelphia chromosome-negative acute lymphoblastic leukemia. Eur J Hematology Populær

3104 downloads

Toft N, Birgens H, Abrahamsson J, Griškevičius L, Hallböök H, Heyman M, Klausen TW, Jónsson ÓG, Palk K, Pruunsild K, Quist-Paulsen P, Vaitkeviciene G, Vettenranta K, Asberg A, Helt LR, Frandsen T, Schmiegelow K.

default Trends in hematological cancer in the elderly in Denmark, 1980-2012. Acta Oncology Populær

3565 downloads

Ocias LF, Larsen TS, Vestergaard H, Friis LS, Abildgaard N, Frederiksen H

default Early warning and prevention of pneumonia in acute leukemia by patient education, spirometry, and positive expiratory pressure: A randomized controlled trial. Am J Hematology Populær

2984 downloads

Møller T, Moser C, Adamsen L, Rugaard G, Jarden M, Bøtcher TS, Wiedenbein L, Kjeldsen L

default Outpatient management of intensively treated acute leukemia patients- the patients’ perspective. Supportive Care Cancer Populær

3302 downloads

Jepsen LØ, Høybye MT, Hansen DG, Marcher CW, Friis LS.

default Epidemiology and Clinical Significance of Secondary and Therapy-Related Acute Myeloid Leukemia: A National Population-Based Cohort Study. JCO Populær

3465 downloads

Granfeldt Østgård LS, Medeiros BC, Sengeløv H, Nørgaard M, Andersen MK, Dufva IH, Friis LS, Kjeldsen E, Marcher CW, Preiss B, Severinsen M, Nørgaard JM.

default Arsenic trioxide and all-trans retinoic acid treatment for acute promyelocytic leukaemia in all risk groups (AML 17): results of a randomised, controlled, phase 3 trial. Lancet Oncology Populær

2855 downloads

Burnett AK, Russell NH, Hills RK, Bowen D, Kell J, Knapper S, Morgan YG, Lok J, Grech A, Jones G, Khwaja A, Friis L, McMullin MF, Hunter A, Clark RE, Grimwade D; UK National Cancer Research Institute Acute Myeloid Leukaemia Working Group.

default Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients. Genes Populær

3323 downloads

Helbo AS, Treppendahl M, Aslan D, Dimopoulos K, Nandrup-Bus C, Holm MS, Andersen MK, Liang G, Kristensen LS, Grønbæk K.

default Validation of the revised international prognostic scoring system (IPSS-R) in patients with lower-risk myelodysplastic syndromes: a report from the prospective European LeukaemiaNet MDS (EUMDS) registry. Br J Hematology Populær

2995 downloads

de Swart L, Smith A, Johnston TW, Haase D, Droste J, Fenaux P, Symeonidis A, Sanz G, Hellström-Lindberg E, Cermák J, Germing U, Stauder R, Georgescu O, MacKenzie M, Malcovati L, Holm MS, Almeida AM, Mądry K, Slama B, Guerci-Bresler A, Sanhes L, Beyne-Rauzy O, Luño E, Bowen D, de Witte T.

default Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia. Blood. Populær

4092 downloads

Dennis M, Russell N, Hills RK, Hemmaway C, Panoskaltsis N, McMullin MF,
Kjeldsen L, Dignum H, Thomas IF, Clark RE, Milligan D, Burnett AK.

default Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation. Oncotarget Populær

3247 downloads

Ørskov AD, Treppendahl MB, Skovbo A, Holm MS, Friis LS, Hokland M, Grønbæk K.

default A randomised comparison of daunorubicin 90mg/m2 vs 60mg/m2 in AML induction: results from the UK NCRI AML17 trial in 1206 patients. Blood Populær

4900 downloads

Burnett AK, Russell NH, Hills RK, Kell J, Cavenagh J, Kjeldsen L, McMullin MF, Cahalin P, Dennis M, Friis L, Thomas IF, Milligan D, Clark RE.

default A comparative assessment of the curative potential of reduced intensity allografts in acute myeloid leukaemia. Leukemia Populær

7062 downloads

Russell NH, Kjeldsen L, Craddock C, Pagliuca A, Yin JA, Clark RE, Howman A,
Hills RK, Burnett AK.

default Impact of chemotherapy delay on short- and long-term survival in younger and older AML patients: a Danish population-based cohort study. Leukemia Populær

4015 downloads

Ostgard LS, Nørgaard JM, Sengeløv H, Holm MS, Jensen MK, Kallenbach M, Marcher CW, Nielsen OJ, Nørgaard M. 

default Comorbidity and performance status in acute myeloid leukemia patients: a nation-wide population-based cohort study. Leukemia. Populær

4083 downloads

Ostgård LS, Nørgaard JM, Sengeløv H, Severinsen M, Friis LS, Marcher CW, Dufva IH, Nørgaard M. 

default Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo. Populær

3320 downloads

Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P, Holm MS, Cazzola M, Malcovati L, Tauro S, Bowen D, Boultwood J, Pellagatti A, Pimanda JE, Unnikrishnan A, Vyas P, Göhring G, Schlegelberger B, Tobiasson M, Kvalheim G, Constantinescu SN, Nerlov C, Nilsson L, Campbell PJ, Sandberg R, Papaemmanuil E, Hellström-Lindberg E, Linnarsson S, Jacobsen SE.

default Complying with the European Clinical Trials directive while surviving the administrative pressure - an alternative approach to toxicity registration in a cancer trial. Eur J Cancer Populær

2765 downloads

Frandsen TL, Heyman M, Abrahamsson J, Vettenranta K, Åsberg A, Vaitkeviciene G, Pruunsild K, Toft N, Birgens H, Hallböök H, Quist-Paulsen P, Griškevičius L, Helt L, Hansen BV, Schmiegelow K.

default Patient Activation through Counseling and Exercise - Acute Leukemia (PACE-AL) -a randomized controlled trial. BMC Cancer. Populær

4303 downloads

Jarden M, Møller T, Kjeldsen L, Birgens H, Christensen JF, Bang Christensen K,, Diderichsen F, Hendriksen C, Adamsen L.

default Optimization of chemotherapy for younger patients with acute myeloid leukemia: results of the medical research council AML15 trial. J Clin Oncol. Populær

3893 downloads

Burnett AK, Russell NH, Hills RK, Hunter AE, Kjeldsen L, Yin J, Gibson BE, Wheatley K, Milligan D. 

default Data quality in the Danish National Acute Leukemia Registry: a hematological data resource. Clin Epidemiol. Populær

8460 downloads

Ostgård LS, Nørgaard JM, Severinsen MT, Sengeløv H, Friis L, Jensen MK, Nielsen OJ, Nørgaard M. 

default Risk group assignment differs for children and adults 1-45 yr with acute lymphoblastic leukemia treated by the NOPHO ALL-2008 protocol. Eur J Hematology Populær

2994 downloads

Toft N, Birgens H, Abrahamsson J, Bernell P, Griškevičius L, Hallböök H, Heyman M, Holm MS, Hulegårdh E, Klausen TW, Marquart HV, Jónsson OG, Nielsen OJ, Quist-Paulsen P, Taskinen M, Vaitkeviciene G, Vettenranta K, Åsberg A, Schmiegelow K.

default The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management. Leuk Res. Populær

3855 downloads

Jarden M, Adamsen L, Kjeldsen L, Birgens H, Tolver A, Christensen JF, Stensen M, Sørensen VA, Møller T.

default Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia. J Clin Oncol. Populær

3400 downloads

Burnett AK, Russell NH, Hills RK, Kell J, Freeman S, Kjeldsen L, Hunter AE, Yin J, Craddock CF, Dufva IH, Wheatley K, Milligan D.

default Durable complete remission after azacitidine treatment in a patient with erythroleukaemia. Eur J Haematol. Populær

3754 downloads

Hansen SB, Dufva IH, Kjeldsen L.

default Health related quality of life and impact of infectious comorbidity in outpatient management of patients with acute leukemia. Leuk Lymphoma. Populær

3499 downloads

Møller T, Adamsen L, Appel C, Welinder P, Stage M, Jarden M, Hjerming M, Kjeldsen L. 

default Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML. Blood. Populær

3617 downloads

Treppendahl MB, Qiu X, Søgaard A, Yang X, Nandrup-Bus C, Hother C, Andersen MK, Kjeldsen L, Möllgård L, Hellström-Lindberg E, Jendholm J, Porse BT, Jones PA, Liang G, Grønbæk K.

default Clinical effect of increasing doses of lenalidomide in high-risk myelodysplastic syndrome and acute myeloid leukemia with chromosome 5 abnormalities. Haematologica. Populær

3290 downloads

Möllgård L, Saft L, Treppendahl MB, Dybedal I, Nørgaard JM, Astermark J, Ejerblad E, Garelius H, Dufva IH, Jansson M, Jädersten M, Kjeldsen L, Linder O, Nilsson L, Vestergaard H, Porwit A, Grønbæk K, Hellström-Lindberg E.

default Identification of patients with acute myeloblastic leukemia who benefit from the addition of gemtuzumab ozogamicin: results of the MRC AML15 trial. J Clin Oncol. Populær

3407 downloads

Burnett AK, Hills RK, Milligan D, Kjeldsen L, Kell J, Russell NH, Yin JA, Hunter A, Goldstone AH, Wheatley K.

default Reasons for treating secondary AML as de novo AML. Eur J Haematol. Populær

4090 downloads

Ostgård LS, Kjeldsen E, Holm MS, Brown Pde N, Pedersen BB, Bendix K, Johansen P, Kristensen JS, Nørgaard JM.